MAIZE THYMIDINE KINASE ACTIVITY IS PRESENT THROUGHOUT PLANT DEVELOPMENT AND ITS HETEROLOGOUS EXPRESSION CONFERS TOLERANCE TO AN ORGANELLAR DNA-DAMAGING AGENT

Maize Thymidine Kinase Activity Is Present throughout Plant Development and Its Heterologous Expression Confers Tolerance to an Organellar DNA-Damaging Agent

Thymidine kinase 1 (TK1) phosphorylates thymidine nucleosides to generate thymidine monophosphate.This reaction belongs to the pyrimidine salvage route that is phylogenetically conserved.In the model plant Arabidopsis thaliana, TK activity contributes to maintain nuclear and organellar genome integrity by providing deoxythymidine-triphosphate (dTTP

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Lewy and his inclusion bodies: Discovery and rejection

ABSTRACT Fritz Jacob Heinrich Lewy described the pathology of Paralysis agitans [Parkinson disease] and was the first to identify eosinophilic inclusion bodies in neurons of certain brain nuclei, later known as Lewy bodies, the pathological signature of the Lewy body diseases.In 1912, he published his seminal study, followed soon after by an update

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